SYNTHESIS OF CURCUMIN DERIVATIVES WITH A CHELATING GROUP FOR THE COMPLEXITY OF METALS AND RADIONUCLIDES
CATEGORY
C07D
AVAILABILITY
available
PATENT PHASE
Recognised patent on date 17/03/2020
INVENTOR
Dr. Mattia Asti – Manager of Radiopharmaceuticals Unit
Dr. Pier Cesare Capponi – no longer pertaining to the Authority
Dr. Michele Iori – Radiopharmaceuticals Unit
Dr. Sara Rubagotti – no longer pertaining to the USL-IRCCS-RE
FIELD OF INTEREST
New molecules used as precursors for radiopharmaceuticals for the diagnosis of cancer and Alzheimer’s disease and related complexes with radioactive and other metals.
DESCRIPTION
A compound obtained from the reaction between a metal-chelating agent and a curcuminoid (i.e. curcumin or a derivative thereof) is described. The invention also relates to the use of such compound for preparing a complex with at least one radioactive or non-radioactive metal through a complexation reaction of the compound with said metal. The complex thus obtained is used for the diagnosis or treatment of diseases, in particular cancer and Alzheimer’s disease.
HOLDER
AUSL-IRCCS with registered office in Via Amendola n. 2 in Reggio Emilia
Sold to third parties on 30 May 2019.
DOCUMENTS
Patent certificate n. 102018000002279
Ultimo aggiornamento: 22/09/21